Metabolic Bone Disease
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http://www.wheelessonline.com/ortho/rickets
Wheeless' Textbook of Orthopaedics
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- Osteomalacia:
- Vit D Abnormalities:
- Discussion:
- rickets is an osteomalacic syndrome in which there is an inability to mineralize chondroid and osteoid;
- lack of available calcium or phosphorus (or both) for mineralization of newly formed osteoid;
- osseous changes in both adults and children reflect the fact that either ionized calcium
or phosphate, or both, is insufficient in concentration to mineralize the skeleton fully;
- there is less mineralized bone per unit volume of bone;
- osseous changes in the rapidly growing skeleton of a young child w/ rickets may result in bowing
deformities due to the decreased resistance of the skeleton to bending and shearing moments;
- as consequence, stress frxs w/ resultant deformities occur;
- note that the classic changes of rickets will typically occur in children younger than 6-7 years of age;
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