Adult Soft Tissue Sarcoma (PDQ®): Treatment
Soft tissue sarcomas are malignant tumors that may arise in any of the mesodermal tissues of the extremities (50%), trunk and retroperitoneum (40%), or head and neck (10%). Rarely, these tumors arise in the gastrointestinal tract or gastrointestinal stroma. Soft tissue sarcomas occur with greater frequency in patients with:

• von Recklinghausen’s disease (neurofibromatosis).
• Gardner’s syndrome.
• Werner’s syndrome.
• Tuberous sclerosis.
• Basal cell nevus syndrome.
• Li-Fraumeni syndrome (p53 mutations).

Childhood Soft Tissue Sarcoma (PDQ®): Treatment
This cancer treatment information summary provides an overview of the prognosis, diagnosis, classification, and treatment of childhood soft tissue sarcoma.

This is a rare sarcoma but is important from the standpoint that under the microscope, it can mimic many benign and malignant conditions. As the name also suggests, it has microscopic features that can sometimes resemble a carcinoma. Unlike most sarcomas, it has a propensity to spread to lymph nodes.