Abstract The etiology of slipped capital femoral epiphysis is still unknown. Traumatic, endocrine, toxic, and mechanical causes have all been hypothesized. It is well documented that the highest incidence occurs during the adolescent growth spurt, suggesting the role of an endocrine abnormality. We report a case that supports this hypothesis Skeletal Radiology Volume 26, Number 3 / March, 1997 Authors A. Feydy, R. Y. Carlier, D. Mompoint, G. Rougereau, A. Patel, C. Vallée

Abstract A collection of 893 historical picture postcards from 1900 to 1935, depicting dwarfs and giants, was analysed from medical and psychosocial viewpoints. In conditions such as 'bird headed dwarfism', achondroplasia, cretinism, so-called Aztecs or pinheads, Grebe chondrodysplasia, and acromegalic gigantism, the disorder could be diagnosed easily. In hypopituitary dwarfism, exact diagnosis was more difficult because of heterogeneity. The most common conditions depicted were pituitary dwarfism and achondroplasia. Most of those with gigantism had pituitary gigantism and acromegaly. Brothers and sisters or parents and their children provided evidence of mendelian inheritance of some of these disorders. The cards suggest that being put on show provided, at least in some cases, social benefits. Full text available A Enderle J R Soc Med. 1998 May; 91(5): 273–278.

Article by Robert Ferry MD

Search String "gigantism"[MeSH Terms]

Abstract Twenty-eight patients with limb overgrowth and the diagnosis of Klippel-Trenaunay-Weber or Proteus syndromes were evaluated retrospectively. These disorders are part of the phakomatosis spectrum of syndromes. The orthopedic problems consisted of asymmetric limb overgrowth, localized gigantism, angular deformities, scoliosis, vascular malformations, and skin anomalies. Systemic abnormalities are common and deserve full evaluation before treatment. Surgical treatment consisted of epiphysiodesis, osteotomies, debulking procedures, and amputation. Mixed results were obtained with surgery, and conservative or supportive treatment should be the primary mode of orthopedic care GUIDERA K. J. (1) ; BRINKER M. R. ; KOUSSEFF B. G. ; HELAL A. A. (1) ; PUGH L. I. (1) ; GANEY T. M. (1) ; OGDEN J. A. (1) ; Journal of pediatric orthopedics 1993, vol. 13, no 4, pp. 538-554 (38 ref.), pp. 459-466